There are outdoor activities to add to your bucket list of things to do in Cherokee, NC, as well as various restaurants, museums and parks.įor a fun vacation, Let’s explore the top things to do in Cherokee, North Carolina. You can learn of the Cherokee tribe, historical sites and interesting cultural spots. It is popular for accommodating the remnants of tribal history and is the base of the Eastern Band of Cherokee Indians. It is named after the early settlers -Cherokee people- who have more than 10,000 years of history in this great location. Located in the Oconaluftee River Valley, Cherokee is a small town in North Carolina, near the southern entrance of Great Smoky Mountain National Park.